Category: ADCY5

ADCY5‑related movement disorder is a rare genetic neurological condition that causes involuntary movements due to changes in the ADCY5 gene, which plays an important role in signaling pathways in the brain that help control movement. People with this disorder often experience episodes of rapid, irregular movements such as chorea, dystonia, or myoclonus, which can affect the face, arms, legs, or trunk. These movements may worsen during periods of stress, excitement, or fatigue and are often more noticeable at night or during transitions between sleep and waking. Symptoms typically begin in childhood and can vary widely in severity from person to person. Although ADCY5-related movement disorder is not degenerative like some neurological diseases, the unpredictable movements can significantly impact daily activities. Researchers continue to study the condition to better understand how the gene affects brain signaling and to develop treatments that can help manage symptoms.