Category: GNAO1

GNAO1-related disorder is a rare genetic neurological condition caused by mutations in the GNAO1 gene, which plays a key role in how brain cells send and regulate signals. When this gene is altered, it disrupts communication between neurons, leading to symptoms that often begin in infancy or early childhood. These can include severe developmental delay, epilepsy, and hyperkinetic movement disorders such as chorea, dystonia, and involuntary jerking movements.